Adams Oliver Syndrome

Definition

Definition of Adams Oliver Syndrome
Adams–Oliver syndrome (AOS) is a rare congenital disorder characterized by defects of the scalp and cranium (cutis aplasia congenita), transverse defects of the limbs, and mottling of the skin.

Symptoms

Symptoms of Adams Oliver Syndrome
The list of signs and symptoms for Adams-Oliver Syndrome:

1. Growth deficiency
2. Abnormal membranous skin patches on scalp
3. Bone defect under abnormal scalp skin patches
4. Foot defects
5. Hand defects
6. Finger defects
7. Toe defects
8. Short fingers
9. Small toenails
10. Cutis marmorata
11. Lower leg defects
12. Short toes
13. Absent fingers
14. Absent toes
15. Absent foot
16. Absent hand
17. Missing bone sections of finger
18. Missing bone sections of toe
19. Hairless scarred patches of scalp
20. Patches of dilated blood vessels under scalp lesions
21. Skull bone defect
22. Absend lower legs
23. Absent hands

Causes

Causes of Adams Oliver Syndrome
To research the causes of Adams-Oliver Syndrome:

1. Congenital disorder
2. Sutosomal recessive disorder
3. Utosomal dominant disorder
4. Mental retardation
5. Scalp anomalies

Diagnosis

Diagnosis of Adams Oliver Syndrome
The diagnosis of AOS is a clinical diagnosis based on the specific features described above. A system of major and minor criteria was proposed.

The combination of two major criteria would be sufficient for the diagnosis of AOS, while a combination of one major and one minor feature would be suggestive of AOS. There is currently no genetic testing that can be performed in order to confirm or rule out this condition.

Treatment

Treatment of Adams Oliver Syndrome
Management of AOS is largely symptomatic and aimed at treating the various congenital anomalies present in the individual. When the scalp and/or cranial bone defects are severe, early surgical intervention with grafting is indicated.

Prognosis

Prognosis of Adams Oliver Syndrome
The overall prognosis is excellent in most cases. However, individuals with more severe scalp and cranial defects may experience complications such as hemorrhage and meningitis, leading to long-term disability.

Prevention

Prevention of Adams Oliver Syndrome
Consult with your doctor.