Aromatase

Definition

Definition of Aromatase
Aromatase is an enzyme responsible for a key step in the biosynthesis of estrogens. It is a member of the cytochrome P450 superfamily (EC 1.14.14.1), which are monooxygenases that catalyze many reactions involved in steroidogenesis. In particular, aromatase is responsible for the aromatization of androgens into estrogens. The aromatase enzyme can be found in many tissues including gonads, brain, adipose tissue, placenta, blood vessels, skin, bone, and endometrium, as well as in tissue of endometriosis, uterine fibroids, breast cancer, and endometrial cancer. It is an important factor in sexual development. Some bodybuilders taking steroids also take antiaromatase supplements to prevent excess testosterone conversion into estrogens, which can cause gynecomastia.

Symptoms

Symptoms of Aromatase
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Causes

Causes of Aromatase
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Diagnosis

Diagnosis of Aromatase
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Treatment

Treatment of Aromatase
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Prognosis

Prognosis of Aromatase
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Prevention

Prevention of Aromatase
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