Arthrogryposis (Epileptic Seizures Migrational Brain Disorder)

Definition

Definition of Arthrogryposis (Epileptic Seizures Migrational Brain Disorder)
Arthrogryposis multiplex congenita (AMC) may be associated with multiple developmental defects. In some severely affected newborns with AMC, autopsy studies have suggested a common mechanism of malmigration at the spinal and cerebral levels. To our knowledge, a constellation of arthrogryposis, epileptic seizures, and brain migrational anomalies in adult patients has not previously been described in a clinical material.

Symptoms

Symptoms of Arthrogryposis (Epileptic Seizures Migrational Brain Disorder)
The list of signs and symptoms for Arthrogryposis (Epileptic Seizures Migrational Brain Disorder) listed below:

1. Narrow palate
2. Amyotrophy
3. Muscle agenesis
4. Seizures
5. Coarse hair
6. Thick hair
7. Torticollis
8. Dense scalp hair
9. Facial structural asymmetry
10. Hairy patch
11. Highly arched palate
12. Mild mental retardation
13. Ptosis

Causes

Causes of Arthrogryposis (Epileptic Seizures Migrational Brain Disorder)
It can be caused by fetal exposure to alcohol or chemical products.

Diagnosis

Diagnosis of Arthrogryposis (Epileptic Seizures Migrational Brain Disorder)
To date, no prenatal diagnostic tools are available to test for the condition. Diagnosis is only used to rule out other causes. This is done by undertaking muscle biopsies, blood tests and general clinical findings rule out other disorders and provides evidence for AMC.

Treatment

Treatment of Arthrogryposis (Epileptic Seizures Migrational Brain Disorder)
While there is no reversal of this condition, individual quality of life can be greatly improved. As each person will respond differently, and will have different needs, a combination of therapies is beneficial. Physical therapy including stretching, strengthening, and mobility training are often provided to improve flexion and range of motion to increase mobility. Occupational therapy (may also include casting, splinting of affected joints) can include training in ADL and fine motor skills as well as addressing psychosocial and emotional implications of living with a disability. Since there is a variety of mobility impairments, individually tailored orthopaedic correction is often beneficial. Orthopedic surgery, which include osteotomy or external Ilizarov fixator, may be elected to correct severely affected joints and limbs and symptoms such as clubfoot, hernia repair and correction of unilateral hip dislocation, in cases where these surgeries improve quality of life. However, in most cases, the contractures would recur despite surgery. A surgery called Tendon Release is usually done to stretch out the tendon the makes most patients walk on their toes.

Prognosis

Prognosis of Arthrogryposis (Epileptic Seizures Migrational Brain Disorder)
Consult with your doctor.

Prevention

Prevention of Arthrogryposis (Epileptic Seizures Migrational Brain Disorder)
Consult with your doctor.