Arthrogryposis (Multiplex Congenita Distal X-Linked)

Definition

Definition of Arthrogryposis (Multiplex Congenita Distal X-Linked)
Arthrogryposis multiplex congenita (AMC) is a term used to describe the presence of two or more (multiplex) joint contractures (arthrogryposis) present at birth (congenita). A joint contracture is a limitation of the normal range of motion of a joint.

Symptoms

Symptoms of Arthrogryposis (Multiplex Congenita Distal X-Linked)

1. Short neck
2. Short nose
3. Abnormal gait
4. Camptodactyly
5. Restricted joint mobility

Causes

Causes of Arthrogryposis (Multiplex Congenita Distal X-Linked)
X-linked arthrogryposis is an X-linked trait caused by a mutation on a gene that has been localized to Xp11.3-p11.2. Neurogenic arthrogryposis has been linked to both an X-linked trait and a trait caused by a gene mutation on the long arm of chromosome 5.

Diagnosis

Diagnosis of Arthrogryposis (Multiplex Congenita Distal X-Linked)
When AMC is complicated by involvement of the central nervous system, approximately half of affected individuals die in infancy. Among the surviving half, many have varying degrees of mental retardation.

Treatment

Treatment of Arthrogryposis (Multiplex Congenita Distal X-Linked)
Consult with your doctor.

Prognosis

Prognosis of Arthrogryposis (Multiplex Congenita Distal X-Linked)
Consult with your doctor.

Prevention

Prevention of Arthrogryposis (Multiplex Congenita Distal X-Linked)
Consult with your doctor.