Arthrogryposis (Multiplex Congenita Distal)

Definition

Definition of Arthrogryposis (Multiplex Congenita Distal)
Arthrogryposis multiplex congenita is a collective term applied to a very large number of different syndromes characterised by non-progressive, multiple joint contractures present at birth. The joints usually develop normally in early embryonic life but as gestation progresses, movements are required to facilitate normal development.

Symptoms

Symptoms of Arthrogryposis (Multiplex Congenita Distal)
Consult with your doctor.

Causes

Causes of Arthrogryposis (Multiplex Congenita Distal)
Causes may be considered to be environmental (lack of ability to move) or genetic (single gene conditions). Causes may be part of a more complex disorder. Underlying neurological or myopathic disorders are very common. The basic cause is fetal akinesia (reduced fetal movements).

Diagnosis

Diagnosis of Arthrogryposis (Multiplex Congenita Distal)

1. Disorders characterised mainly by limb involvement
2. Disorders that involve the limbs and other body parts
3. Disorders with limb involvement and CNS dysfunction
4. Other associated syndromes and conditions

Treatment

Treatment of Arthrogryposis (Multiplex Congenita Distal)
Consult with your doctor.

Prognosis

Prognosis of Arthrogryposis (Multiplex Congenita Distal)
Consult with your doctor.

Prevention

Prevention of Arthrogryposis (Multiplex Congenita Distal)
Genetic advice may be essential to prevent arthrogryposis. Extrinsically derived contractures have a low recurrence risk, but the recurrence risk for intrinsically derived contractures depends on aetiology and ranges from 3% to 50%.