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Behcet Syndrome

Definition


Definition of Behcet Syndrome
Behcet's syndrome is a disease that involves inflammation of the blood vessels. It causes problems in many parts of the body.

Symptoms


Symptoms of Behcet Syndrome
The most common symptoms are:

  1. Sores in the mouth
  2. Sores on the sex organs
  3. Other skin sores
  4. Swelling of parts of the eye
  5. Pain, swelling and stiffness of the joints

Causes


Causes of Behcet Syndrome
Doctors don't know what causes Behcet's disease. However, a combination of genetic and environmental factors likely plays a role. Several genes have been found to be associated with the disease. Some researchers believe a virus or bacterium may trigger Behcet's disease in people who have certain genes that make them susceptible to Behcet's.

Diagnosis


Diagnosis of Behcet Syndrome
Behcet's syndrome is diagnosed based on the finding of recurrent mouth ulcerations combined with any two of the following: eye inflammation, genital ulcerations, or skin abnormalities mentioned above. A special skin test called a pathergy test can also suggest Behcet's syndrome. (The other criteria above are still required for ultimate diagnosis.) This test consists of pricking the skin of the forearm with a sterile needle. The test is called positive and suggests Behcet's syndrome when the puncture causes a sterile red nodule or pustule that is greater than two millimeters in diameter at 24 to 48 hours. Tests such as skin biopsy, lumbar puncture, MRI scan of the brain, and bowel tests are considered based upon symptoms that are present.

Treatment


Treatment of Behcet Syndrome
No cure exists for Behcet's disease. If your signs and symptoms of Behcet's disease are mild, your doctor may offer medications to control temporary flares in pain and inflammation. You may not need to take medication between flares. But if your signs and symptoms are more severe, your doctor may advise systemic medications to control the signs and symptoms of Behcet's disease throughout your body, in addition to medications for the temporary flares. Several factors, including your age and sex, may influence the specific treatment your doctor recommends.

Prognosis


Prognosis of Behcet Syndrome
Consult with your doctor.

Prevention


Prevention of Behcet Syndrome
Consult with your doctor.


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