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Colonic Atresia

Definition


Definition of Colonic Atresia
Colonic atresia is an intestinal atresia which may present in the newborn period.

Symptoms


Symptoms of Colonic Atresia
Consult with your doctor.

Causes


Causes of Colonic Atresia
Colonic atresia occurs in 1:20,000 live births, offering a neonatal surgical challenge. Prenatal expression of fibroblast growth factor 10 (Fgf10), acting through fibroblast growth factor receptor 2b (Fgfr2b), is critical to the normal development of the colon. Invalidation of the Fgf10 pathway results in colonic atresia, inherited in an autosomal recessive pattern. Classically, disturbance of the mesenteric vasculature has been thought to cause many forms of intestinal atresia. The purpose of this study was to evaluate the role of vascular occlusion in the pathogenesis of colonic atresia.

Diagnosis


Diagnosis of Colonic Atresia
Consult with your doctor.

Treatment


Treatment of Colonic Atresia
Treatment requires surgical repair.

Prognosis


Prognosis of Colonic Atresia
Consult with your doctor.

Prevention


Prevention of Colonic Atresia
Consult with your doctor.


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